Fifty-seven patients were evaluated objectively for cerebral vascular arterial occlusion before and after an average of 28 intravenous infusions of disodium ethylene diamine tetra-acetic acid. Measurements of arterial occlusion were made with the relatively simple, noninvasive oculocerebrovasculometric analysis. Cerebrovascular arterial occlusion diminished by an average of 18% (from a mean of 28% to a mean of 10 %) following therapy (P<0.001). Eighty-eight percent of patients treated with EDTA chelation therapy showed objective improvements in cerebrovascular blood flow.